Crafting stations
- Runecrafting altar (catalytic)
- Runecrafting altar (Dungeoneering)
- Runecrafting altar (elemental)
- runite rock
- Safalaan Hallow (statue)Statue plinth
- Safta Doc
- Sailor
- Salty water
- Sand (scenery)
- Sandpit
- Sani Piliu (statue)Statue plinth
- Saradomin Altar
- Sarcophagus (The Barrows Brothers)Ahrim
- Sarcophagus (The Barrows Brothers)Dharok
- Sarcophagus (The Barrows Brothers)Guthan
- Sarcophagus (The Barrows Brothers)Karil
- Sarcophagus (The Barrows Brothers)Torag
- Sarcophagus (The Barrows Brothers)Verac
- Sawmill
- Sawmill operator
- Sbott
- Scrimshaw Crafter
- Seiryu the Azure SerpentShadow Reef
- Sharp rock
- Shield painting easel
- Sigli the Huntsman
- Singing bowl (Bolrie's lab)
- Singing bowl (Brimstail's home)
- Singing bowl (Ithell district)
- Singing bowl (Yewnock's cave)
- Sink (Twilight of the Gods)
- Sithik Ints
- Skulgrimen
- Sky-blue poison frogBig Game Hunter
- Slayer Rewards
- Slot (Elemental Workshop)
- Small oven
- Small pedestal
- Small pedestal (limestone)
- Small pedestal (mahogany)
- Smashing Pumpkin (Harvest Hollow)
- Smith
- Soft metal anvil
- Soul altar
- Soul forge
- Soup creation station
- Sparkling pool (Succession)
- Sparkling spring