| Cockroach worker [] | 1 | 4.38/1,000 |
| Columbarium key [] | 1 | 55.3/1,000 |
| Commander Zilyana (Hard mode) [] | 1 | 161/1,000 |
| Commander Zilyana (Normal mode) [] | 1 | 161/1,000 |
| Cooper (Normal mode) [] | 1 | 255/1,000 |
| Corporeal Beast [] | 13 | 382/1,000 |
| Corrupted dust devil [] | 1 | 8.96/1,000 |
| Corrupted kalphite guardian [] | 1 | 8.96/1,000 |
| Corrupted kalphite marauder [] | 1 | 8.96/1,000 |
| Corrupted lizard [] | 1 | 8.96/1,000 |
| Corrupted scarab [] | 1 | 8.96/1,000 |
| Corrupted scorpion [] | 1 | 8.96/1,000 |
| Corrupted worker [] | 1 | 8.96/1,000 |
| Cow [] | 1 | 0.498/1,000 |
| Crassian Leviathan (Normal mode) [] | 1 | 255/1,000 |
| Crassian scout (Normal mode) [] | 1 | 255/1,000 |
| Crassian scuttler (Normal mode) [] | 1 | 255/1,000 |
| Crassian warrior (Normal mode) [] | 1 | 255/1,000 |
| Crawling hand [] | 1 | 0.616/1,000 |
| Crocodile akh [] | 1 | 8.96/1,000 |
| Croesus (Active) [] | 20 | 377/1,000 |
| Cyclossus [] | 1 | 76.8/1,000 |
| Dagannoth [] | 1 | 7.12/1,000 |
| Dagannoth [] | 1 | 8.5/1,000 |
| Dagannoth (Level 77) [] | 1 | 9.75/1,000 |
| Dagannoth (Level 78) [] | 1 | 8.06/1,000 |
| Dark beast [] | 1 | 134/1,000 |
| Dark beast [] | 1 | 134/1,000, 3 rolls |
| Dark wizard (The Zamorakian Undercity) (Normal mode) [] | 1 | 255/1,000 |
| Dark wizard elder (Normal mode) [] | 1 | 255/1,000 |
| Dark wizard master (Normal mode) [] | 1 | 255/1,000 |
| Death Lotus rogue (Elite Dungeons) (Temple of Aminishi (Normal mode)) [] | 1 | 255/1,000 |
| Death Lotus rogue (Elite Dungeons) (The Shadow Reef (Normal mode)) [] | 1 | 255/1,000 |
| Deathbreath (Normal mode) [] | 1 | 255/1,000 |
| Desert strykewyrm [] | 1 | 7.47/1,000 |
| Devil's snare [] | 1 | 255/1,000 |
| Divine Druid (Equilibrium League) (Equilibrium Leagues) [] | 6–14 | 1/23 |
| Divine fire spirit (Divine) [] | 1 | Uncommon |
| Divine forge phoenix (Divine phoenix) [] | 1 | Uncommon |
| Dragon wolf alpha (Normal mode) [] | 1 | 255/1,000 |
| Dragonstone dragon [] | 3 | 13.4/1,000 |
| Dragonstone dragon (Dragonkin Laboratory) (Normal mode) [] | 1 | 255/1,000 |
| Dried zombie (Dried) [] | 1 | 51.4/1,000 |
| Dried zombie (Parched) [] | 1 | 55.2/1,000 |
| Dried zombie (Unmoisturised) [] | 1 | 52.3/1,000 |
| Dust devil [] | 1 | 8.09/1,000 |
| Dust devil [] | 1 | 8.09/1,000, 3 rolls |
| Dwarf (Level 9) [] | 1 | 5.84/1,000 |