| Ogress [] | 1 | 6.54/1,000 |
| Ogress champion [] | 1 | 7.7/1,000 |
| Ogress warrior [] | 1 | 5.56/1,000 |
| Ol' Sawtooth (Normal mode) [] | 1 | 255/1,000 |
| Olivia the Chronicler (Normal mode) [] | 1 | 255/1,000 |
| Onyx dragon [] | 1 | 13.4/1,000 |
| Onyx dragon (Dragonkin Laboratory) (Normal mode) [] | 1 | 255/1,000 |
| Oreb, the Magister (Normal mode) [] | 1 | 255/1,000 |
| Oyu the Quietest (Normal mode) [] | 1 | 255/1,000 |
| Pee Hat [] | 1 | 10.4/1,000 |
| Pirate plunder [{'content': 'Estimated rarity may be inaccurate due to a low sample size.', 'name': 'inaccurate'}] | 25 | 5/267 |
| Pirate plunder (small) [{'content': 'Estimated rarity may be inaccurate due to a low sample size.', 'name': 'inaccurate'}] | 25 | 5/267 |
| Possessed pickaxe (Lair of Tarn Razorlor) [] | 1 | 18.7/1,000 |
| Profane Scabarite [] | 2 | 10/100 |
| Pyrefiend [] | 1 | 2.32/1,000 |
| Pyrefiend [] | 1 | 2.32/1,000 |
| Quetzathog (Normal mode) [] | 1 | 255/1,000 |
| Raptor's chest of slaying [] | 75 | Always |
| Ravenous ghoul [] | 1 | 9.97/1,000 |
| Red dragon [] | 1 | 36.2/1,000 |
| Red dragon (Dragonkin Laboratory) (Normal mode) [] | 1 | 255/1,000 |
| Reinforced chest (Dorgesh-Kaan) [] | 1–2 | Common |
| Renegade Menaphite soldier (Normal mode) [] | 1 | 255/1,000 |
| Ripper Demon [] | 4 | 249/1,000 |
| Ripper dinosaur [] | 1 | 255/1,000 |
| Rock [] | 1 | 10.4/1,000 |
| Rock crab [] | 1 | 1.81/1,000 |
| Rock lobster [] | 2 | 9.4/1,000 |
| Rogue [] | 1 | 1.26/1,000 |
| Rorarius [] | 1 | 6.74/1,000 |
| Rune dragon [] | 4 | 51.8/1,000 |
| Salawa akh [] | 1 | 8.96/1,000 |
| Sangri the Red (Normal mode) [] | 1 | 255/1,000 |
| Sanguine crawler [] | 1 | 5.3/1,000 |
| Sarkhan the Serpentspeaker (Normal mode) [] | 1 | 255/1,000 |
| Scarab akh [] | 1 | 8.96/1,000 |
| Scutarius [] | 1 | 241/1,000 |
| Sea crocodile (Normal mode) [] | 1 | 255/1,000 |
| Sea horror (Normal mode) [] | 1 | 255/1,000 |
| Seeker [] | 1 | 8.96/1,000 |
| Seiryu the Azure Serpent (Normal mode) [] | 1 | 255/1,000 |
| Shadow warrior [] | 1 | 5.32/1,000 |
| Shiny columbarium key [] | 1 | 55.3/1,000 |
| Shrine Maiden Elei (Normal mode) [] | 1 | 255/1,000 |
| Shul the Molten (Normal mode) [] | 1 | 255/1,000 |
| Skeletal hand [] | 1 | 3.36/1,000 |
| Skeletal Wyvern [] | 2 | 13.7/1,000 |
| Skeleton (Level 45) [] | 1 | 19.9/1,000 |