| Cooper (Normal mode) [] | 1–3 | 1/40 |
| Cooper (Normal mode) [] | 270–330 | 1/76,800 |
| Corporeal Beast [] | 270–330 | 1/3,355,443.2, 10 rolls |
| Corrupted dust devil [] | 270–330 | 1/76,800 |
| Corrupted kalphite guardian [] | 270–330 | 1/76,800 |
| Corrupted kalphite marauder [] | 270–330 | 1/76,800 |
| Corrupted lizard [] | 270–330 | 1/76,800 |
| Corrupted scarab [] | 270–330 | 1/76,800 |
| Corrupted scorpion [] | 270–330 | 1/76,800 |
| Corrupted worker [] | 270–330 | 1/76,800 |
| Crassian Leviathan (Normal mode) [] | 1–3 | 1/40 |
| Crassian Leviathan (Normal mode) [] | 270–330 | 1/76,800 |
| Crassian scout (Normal mode) [] | 270–330 | 1/76,800 |
| Crassian scout (The Shadow Reef) (Normal mode (Floor 2)) [] | 1–3 | 1/26.67 |
| Crassian scout (The Shadow Reef) (Normal mode (Floor 3)) [] | 1–3 | 1/44.4 |
| Crassian scuttler (Normal mode) [] | 270–330 | 1/76,800 |
| Crassian scuttler (Normal mode (Floor 2)) [] | 1–3 | 1/26.67 |
| Crassian scuttler (Normal mode (Floor 3)) [] | 1–3 | 1/44.4 |
| Crassian warrior (Normal mode) [] | 270–330 | 1/76,800 |
| Crassian warrior (The Shadow Reef) (Normal mode (Floor 2)) [] | 1–3 | 1/26.67 |
| Crassian warrior (The Shadow Reef) (Normal mode (Floor 3)) [] | 1–3 | 1/44.4 |
| Crawling hand [] | 270–330 | 1/4,194,304 |
| Crocodile akh [] | 270–330 | 1/76,800 |
| Crystal Shapeshifter (Magic) [] | 270–330 | 1/76,800 |
| Cyclops [] | 270–330 | 1/3,276,800 |
| Cyclops [] | 270–330 | Very rare |
| Cyclops (God Wars Dungeon) [] | 270–330 | 1/3,276,800 |
| Cyclossus [] | 270–330 | 1/102,400 |
| Dagannoth (Lighthouse) [] | 270–330 | 1/8,388,608 |
| Dagannoth guardian [] | 270–330 | 1/1,048,576 |
| Dagannoth Prime [] | 270–330 | 1/71,558.87 |
| Dagannoth Rex [] | 270–330 | 1/71,558.87 |
| Dagannoth spawn [] | 270–330 | 1/8,388,608 |
| Dagannoth Supreme [] | 270–330 | 1/71,558.87 |
| Dagannoth (Melee) [] | 270–330 | 1/8,388,608 |
| Dagannoth (Ranged) [] | 270–330 | 1/8,388,608 |
| Dark animica rock [{'content': 'Only when using a juju mining potion or perfect juju mining potion.'}] | 1 | 1/10 |
| Dark beast [] | 270–330 | 1/102,400 |
| Dark beast [] | 270–330 | 1/51,200, 3 rolls |
| Dark wizard (The Zamorakian Undercity) (Normal mode) [] | 270–330 | 1/76,800 |
| Dark wizard (The Zamorakian Undercity) (Story mode) [] | 3–6 | 200/10,000 |
| Dark wizard elder (Normal mode) [] | 270–330 | 1/76,800 |
| Dark wizard elder (Story mode) [] | 3–6 | 200/10,000 |
| Dark wizard master (Normal mode) [] | 270–330 | 1/76,800 |
| Dark wizard master (Story mode) [] | 3–6 | 200/10,000 |
| Death Lotus rogue [] | 270–330 | 1/4,194,304 |
| Death Lotus rogue (Elite Dungeons) (Temple of Aminishi (Normal mode)) [] | 1 | 1/19.2 |
| Death Lotus rogue (Elite Dungeons) (Temple of Aminishi (Normal mode)) [] | 270–330 | 1/76,800 |