| Eduard [] | 1 | 1/67,108,864 |
| Egg Hunt (Treasure Hunter promotion) [] | 1 | Unknown |
| Egg Hunt (Treasure Hunter promotion)/Archive (From 6 to 12 April 2023) [] | 1 | 16,545,000/1,465,000,000 |
| Elegorn the Celestial (Normal mode) [] | 1 | 1/153,600 |
| Elf warrior (Elf Camp) [] | 1 | 1/3,355,443.2 |
| Elf warrior (Lletya) [] | 1 | 1/3,355,443.2 |
| Elite Black Knight [] | 1 | 1/8,388,608 |
| Elite Dark Ranger [] | 1 | 1/16,777,216 |
| Elite Dark Warrior [] | 1 | 1/16,777,216 |
| Elite Khazard guard [] | 1 | 1/3,744,914.29 |
| Elite Profane Scabarite [] | 1 | 1/153,600 |
| Elite rune dragon [] | 1 | 1/10,240 |
| Elite Sakadagami (Normal mode) [] | 1 | 1/153,600 |
| Elite Sotapanna (Normal mode) [] | 1 | 1/153,600 |
| Emberbound Soul (Normal mode) [] | 1 | 1/153,600 |
| Engorged lava strykewyrm (Normal mode) [] | 1 | 1/153,600 |
| Enlightened Sotapanna (Normal mode) [] | 1 | 1/153,600 |
| Enraged barbarian spirit [] | 1 | 1/8,060,928 |
| Event mystery box (Shifting Sands) [{'content': 'Only if not an Ironman Mode player.', 'name': 'onlymains'}, {'content': 'Estimated rarity may be inaccurate due to a low sample size.', 'name': 'inaccurate'}] | 1 | 26/862, 2 rolls |
| Event mystery box (The Need for Mead) [{'content': 'Estimated rarity may be inaccurate due to a low sample size.', 'name': 'inaccurate'}] | 1 | 27/956, 2 rolls |
| Exiled kalphite guardian [] | 1 | 1/2,796,202.67 |
| Exiled kalphite guardian [] | 1 | 1/204,800 |
| Exiled kalphite marauder [] | 1 | 1/2,796,202.67 |
| Exiled kalphite marauder [] | 1 | 1/204,800 |
| Exiled kalphite paragon [] | 1 | 1/3,355,443.2 |
| Exiled Kalphite Queen [] | 1 | 1/96,509.53, 4 rolls |
| Exiled kalphite soldier [] | 1 | 1/3,355,443.2 |
| Experiment No.2 [] | 1 | 1/2,796,202.67 |
| Eye of Cythan (Normal mode) [] | 1 | 1/153,600 |
| Fallen champion [] | 1 | 1/3,250,585.6 |
| Feline akh [] | 1 | 1/153,600 |
| Feral Dinosaur [] | 1 | 1/102,400 |
| Feral vampyre [] | 1 | 1/4,194,304 |
| Ferocious barbarian spirit [] | 1 | 1/2,097,152 |
| Fire elemental [] | 1 | 1/8,388,608 |
| Fire giant [] | 1 | 1/216,379.69 |
| Firebelly (Normal mode) [] | 1 | 1/153,600 |
| Firework Festival [] | 1 | 1,526,250/121,000,000 |
| Flesh Crawler [] | 1 | 1/6,553,600 |
| Force muspah [] | 1 | 1/153,600 |
| Freidir [] | 1 | 1/67,108,864 |
| Freygerd [] | 1 | 1/67,108,864 |
| Frog [] | 1 | 1/5,592,405.33 |
| Frost dragon [] | 1 | 1/3,355,443.2 |
| Galina [] | 1 | 1/67,108,864 |
| Ganodermic beast [] | 1 | 1/153,600 |
| General Graardor (Hard mode) [] | 1 | 1/102,400 |
| General Graardor (Normal mode) [] | 1 | 1/98,782.48 |