| Shadow demon [] | 1 | 1/3,171,942.4 |
| Shadow nihil [] | 1 | 1/102,400 |
| Shadow warrior [] | 1 | 1/2,097,152 |
| Shining Prismania [] | 1 | 3,825,000/523,512,000 |
| Shrine Maiden Elei (Normal mode) [] | 1 | 1/153,600 |
| Shul the Molten (Normal mode) [] | 1 | 1/153,600 |
| Sir Carl [] | 1 | 1/8,388,608 |
| Sir Harry [] | 1 | 1/8,388,608 |
| Sir Jerro [] | 1 | 1/8,388,608 |
| Skeletal miner [] | 1 | 1/8,388,608 |
| Skeleton (Dark Warriors' Fortress) [] | 1 | 1/8,388,608 |
| Skeleton [] | 1 | 1/16,777,216 |
| Skeleton [] | 1 | 1/3,303,014.4 |
| Skeleton (Tarn's Lair) (High level) [] | 1 | 1/8,388,608 |
| Skeleton (Tarn's Lair) (Low level) [] | 1 | 1/8,388,608 |
| Skeleton (Tarn's Lair) (Medium level) [] | 1 | 1/8,388,608 |
| Skeleton (Ullek) [] | 1 | 1/8,388,608 |
| Skeleton brute [] | 1 | 1/8,060,928 |
| Skeleton fremennik [] | 1 | 1/8,388,608 |
| Skeleton heavy [] | 1 | 1/8,060,928 |
| Skeleton hero [] | 1 | 1/8,060,928 |
| Skeleton Mage [] | 1 | 1/16,777,216 |
| Skeleton Mage (Piscatoris Fishing Colony) [] | 1 | 1/3,145,728 |
| Skeleton thug [] | 1 | 1/8,060,928 |
| Skeleton warlord [] | 1 | 1/8,060,928 |
| Skeleton (Armed) [] | 1 | 1/8,388,608 |
| Skeleton (Unarmed) [] | 1 | 1/16,777,216 |
| Slasher Demon [] | 1 | 1/97,632.77, 3 rolls |
| Small lizard [] | 1 | 1/3,355,443.2 |
| Smoke nihil [] | 1 | 1/102,400 |
| Smouldering Lamps [] | 1 | 525,000/99,550,000 |
| Smouldering vs Supernova [] | 1 | 231,350/49,775,000 |
| Smoulders (Normal mode) [] | 1 | 1/153,600 |
| Smuggler's Spoils [] | 1 | Unknown |
| Sofiya [] | 1 | 1/67,108,864 |
| Soldier [] | 1 | 1/8,388,608 |
| Solstice Showdown [] | 1 | 451,150/99,550,000 |
 Sorebones[] | 1 | 1/16,777,216 |
| Soul Showdown [] | 1 | 451,150/99,550,000 |
| Soulgazer [] | 1 | 1/102,400 |
| Soulgazer [] | 1 | 1/102,400 |
| Speedy Keith [] | 1 | 1/8,388,608 |
| Spiritual mage [] | 1 | 1/1,198,372.57 |
| Spiritual warrior [] | 1 | 1/2,396,745.14 |
| Spyndra (Normal mode) [] | 1 | 1/153,600 |
| Squeal of Fortune/Rewards/Limited [] | 1 | Discontinued |
| Steel dragon [] | 1 | 1/2,796,202.67 |
| Stick [] | 1 | 1/3,355,443.2 |