| Elegorn the Celestial (Story mode) [] | 1 | Always |
| Elf warrior (Elf Camp) [] | 35–45 | 1/104,857.6 |
| Elf warrior (Lletya) [] | 35–45 | 1/104,857.6 |
| Elite Black Knight [] | 35–45 | 1/262,144 |
| Elite Dark Ranger [] | 35–45 | 1/524,288 |
| Elite Dark Warrior [] | 35–45 | 1/524,288 |
| Elite Khazard guard [] | 35–45 | 1/117,028.57 |
| Elite Profane Scabarite [] | 35–45 | 1/4,800 |
| Elite rune dragon [] | 35–45 | 1/320 |
| Elite Sakadagami (Normal mode) [] | 35–45 | 1/4,800 |
| Elite Sotapanna (Normal mode) [] | 35–45 | 1/4,800 |
| Emberbound Soul (Normal mode) [] | 35–45 | 1/4,800 |
| Engorged lava strykewyrm (Normal mode) [] | 35–45 | 1/4,800 |
| Enlightened Sotapanna (Normal mode) [] | 35–45 | 1/4,800 |
| Enraged barbarian spirit [] | 35–45 | 1/251,904 |
| Transmutation (Equilibrium League) [{'content': 'Requires appropriate material to transmute from.'}] | 1–10 | Special |
| Exiled kalphite guardian [] | 35–45 | 1/87,381.33 |
| Exiled kalphite guardian [] | 35–45 | 1/6,400 |
| Exiled kalphite marauder [] | 35–45 | 1/87,381.33 |
| Exiled kalphite marauder [] | 35–45 | 1/6,400 |
| Exiled kalphite paragon [] | 35–45 | 1/104,857.6 |
| Exiled Kalphite Queen [] | 35–45 | 1/3,015.92, 4 rolls |
| Exiled kalphite soldier [] | 35–45 | 1/104,857.6 |
| Experiment No.2 [] | 35–45 | 1/87,381.33 |
| Eye of Cythan (Normal mode) [] | 35–45 | 1/4,800 |
| Fallen champion [] | 35–45 | 1/101,580.8 |
| Feline akh [] | 35–45 | 1/4,800 |
| Feral Dinosaur [] | 35–45 | 1/3,200 |
| Feral vampyre [] | 35–45 | 1/131,072 |
| Ferocious barbarian spirit [] | 35–45 | 1/65,536 |
| Fire elemental [] | 35–45 | 1/262,144 |
| Fire giant [] | 35–45 | 1/6,761.87 |
| Firebelly (Normal mode) [] | 35–45 | 1/4,800 |
| Flesh Crawler [] | 35–45 | 1/204,800 |
| Force muspah [] | 35–45 | 1/4,800 |
| Freezing black dragon [] | 1 | Always |
| Freidir [] | 35–45 | 1/2,097,152 |
| Freygerd [] | 35–45 | 1/2,097,152 |
| Frog [] | 35–45 | 1/174,762.67 |
| Frost dragon [] | 35–45 | 1/104,857.6 |
| Galina [] | 35–45 | 1/2,097,152 |
| Ganodermic beast [] | 35–45 | 1/4,800 |
| General Graardor (Hard mode) [] | 35–45 | 1/3,200 |
| General Graardor (Normal mode) [] | 35–45 | 1/3,086.95 |
| General malpractitioner [] | 35–45 | 1/51,200 |
| Georgy [] | 35–45 | 1/2,097,152 |
 Ghast (Regular)[] | 35–45 | 1/262,144 |
| Ghost treat [] | 15 | Uncommon |