| Cyclops (God Wars Dungeon) [] | 1 | 1/81,920 |
| Cyclops (God Wars Dungeon) [] | 18–22 | 1/4,369,066.67 |
| Cyclossus [] | 1 | 1/2,560 |
| Cyclossus [] | 18–22 | 1/136,533.33 |
| Dagannoth (Lighthouse) [] | 1 | 1/209,715.2 |
| Dagannoth (Lighthouse) [] | 18–22 | 1/11,184,810.67 |
| Dagannoth guardian [] | 1 | 1/26,214.4 |
| Dagannoth guardian [] | 18–22 | 1/1,398,101.33 |
| Dagannoth Prime [] | 1 | 1/1,788.97 |
| Dagannoth Prime [] | 18–22 | 1/95,411.83 |
| Dagannoth Rex [] | 1 | 1/1,788.97 |
| Dagannoth Rex [] | 18–22 | 1/95,411.83 |
| Dagannoth spawn [] | 1 | 1/209,715.2 |
| Dagannoth spawn [] | 18–22 | 1/11,184,810.67 |
| Dagannoth Supreme [] | 1 | 1/1,788.97 |
| Dagannoth Supreme [] | 18–22 | 1/95,411.83 |
| Dagannoth (Melee) [] | 1 | 1/209,715.2 |
| Dagannoth (Melee) [] | 18–22 | 1/11,184,810.67 |
| Dagannoth (Ranged) [] | 1 | 1/209,715.2 |
| Dagannoth (Ranged) [] | 18–22 | 1/11,184,810.67 |
| Dark beast [] | 1 | 1/2,560 |
| Dark beast [] | 18–22 | 1/136,533.33 |
| Dark beast [] | 1 | 1/1,280, 3 rolls |
| Dark beast [] | 18–22 | 1/68,266.67, 3 rolls |
| Dark wizard (The Zamorakian Undercity) (Normal mode) [] | 1 | 1/1,920 |
| Dark wizard (The Zamorakian Undercity) (Normal mode) [] | 18–22 | 1/102,400 |
| Dark wizard elder (Normal mode) [] | 1 | 1/1,920 |
| Dark wizard elder (Normal mode) [] | 18–22 | 1/102,400 |
| Dark wizard master (Normal mode) [] | 1 | 1/1,920 |
| Dark wizard master (Normal mode) [] | 18–22 | 1/102,400 |
| Death Lotus rogue [] | 1 | 1/104,857.6 |
| Death Lotus rogue [] | 18–22 | 1/5,592,405.33 |
| Death Lotus rogue (Elite Dungeons) (Temple of Aminishi (Normal mode)) [] | 1 | 1/1,920 |
| Death Lotus rogue (Elite Dungeons) (Temple of Aminishi (Normal mode)) [] | 18–22 | 1/102,400 |
| Death Lotus rogue (Elite Dungeons) (The Shadow Reef (Normal mode)) [] | 1 | 1/1,920 |
| Death Lotus rogue (Elite Dungeons) (The Shadow Reef (Normal mode)) [] | 18–22 | 1/102,400 |
| Deathbreath (Normal mode) [] | 1 | 1/1,920 |
| Deathbreath (Normal mode) [] | 18–22 | 1/102,400 |
| Demon Boss (Non-Wilderness) [] | 1 | 4/64, 5 rolls |
| Demon Boss (Wilderness) [] | 1 | 3/64, 5 rolls |
| Desert lizard [] | 1 | 1/41,943.04 |
| Desert lizard [] | 18–22 | 1/2,236,962.13 |
| Desert strykewyrm [] | 1 | 1/18,386.49 |
| Desert strykewyrm [] | 18–22 | 1/980,612.74 |
| Devil's snare [] | 1 | 1/1,280 |
| Devil's snare [] | 18–22 | 1/68,266.67 |
| Donny the Lad [] | 1 | 1/104,857.6 |
| Donny the Lad [] | 18–22 | 1/5,592,405.33 |