| Yadviga [] | 135–165 | 1/83,886,080 |
| Yeti [] | 135–165 | 1/3,276,800 |
| Yor'Ger the Deceiver (Normal mode) [] | 135–165 | 1/192,000 |
| Yukimura of Hanto (Normal mode) [] | 135–165 | 1/192,000 |
| Yuri [] | 135–165 | 1/83,886,080 |
 Zamorak, Lord of Chaos[] | 50–72 | 1/13 |
| Zamorakian cultist (Normal mode) [] | 135–165 | 1/192,000 |
| Zamorakian hound master (Normal mode) [] | 135–165 | 1/192,000 |
| Zamorakian hunter (Normal mode) [] | 135–165 | 1/192,000 |
| Zamorakian ritual keeper (Level 107 (Normal mode)) [] | 135–165 | 1/192,000 |
| Zamorakian ritual keeper (Level 115 (Normal mode)) [] | 135–165 | 1/192,000 |
| Zamorakian sniper [] | 135–165 | 1/4,128,768 |
| Zoja [] | 135–165 | 1/83,886,080 |
| Zombie (Lair of Tarn Razorlor) (Levels 72–75) [] | 135–165 | 1/20,971,520 |
| Zombie (Lair of Tarn Razorlor) (Levels 77–79) [] | 135–165 | 1/20,971,520 |
| Zombie (Lair of Tarn Razorlor) (Levels 82–85) [] | 135–165 | 1/20,971,520 |
| Zombie (Stronghold of Security) [] | 135–165 | 1/8,192,000 |
| Zombie (Normal mode) [] | 135–165 | 1/192,000 |
| Zombie (Wilderness) (Level 29) [] | 135–165 | 1/20,971,520 |
| Zombie pirate [] | 135–165 | 1/20,971,520 |
| Zombie pirate (Harmony Island) [] | 135–165 | 1/20,971,520 |
| Zombie swab [] | 135–165 | 1/20,971,520 |
| Zombie (Level 29) [] | 135–165 | 1/20,971,520 |