| Seren spirit [] | 1 | 1/512 |
| Seren warrior [] | 1 | 1/1,651,507.2 |
| Shadow demon [] | 1 | 1/1,585,971.2 |
| Shadow nihil [] | 1 | 1/51,200 |
| Shadow warrior [] | 1 | 1/1,048,576 |
| Shrine Maiden Elei (Normal mode) [] | 1 | 1/76,800 |
| Shul the Molten (Normal mode) [] | 1 | 1/76,800 |
| Sir Carl [] | 1 | 1/4,194,304 |
| Sir Harry [] | 1 | 1/4,194,304 |
| Sir Jerro [] | 1 | 1/4,194,304 |
| Skeletal miner [] | 1 | 1/4,194,304 |
| Skeleton (Dark Warriors' Fortress) [] | 1 | 1/4,194,304 |
| Skeleton [] | 1 | 1/8,388,608 |
| Skeleton [] | 1 | 1/1,651,507.2 |
| Skeleton (Tarn's Lair) (High level) [] | 1 | 1/4,194,304 |
| Skeleton (Tarn's Lair) (Low level) [] | 1 | 1/4,194,304 |
| Skeleton (Tarn's Lair) (Medium level) [] | 1 | 1/4,194,304 |
| Skeleton (Ullek) [] | 1 | 1/4,194,304 |
| Skeleton brute [] | 1 | 1/4,030,464 |
| Skeleton fremennik [] | 1 | 1/4,194,304 |
| Skeleton heavy [] | 1 | 1/4,030,464 |
| Skeleton hero [] | 1 | 1/4,030,464 |
| Skeleton Mage [] | 1 | 1/8,388,608 |
| Skeleton Mage (Piscatoris Fishing Colony) [] | 1 | 1/1,572,864 |
| Skeleton thug [] | 1 | 1/4,030,464 |
| Skeleton warlord [] | 1 | 1/4,030,464 |
| Skeleton (Armed) [] | 1 | 1/4,194,304 |
| Skeleton (Unarmed) [] | 1 | 1/8,388,608 |
| Slasher Demon [] | 1 | 1/48,816.39, 3 rolls |
| Small lizard [] | 1 | 1/1,677,721.6 |
| Smoke nihil [] | 1 | 1/51,200 |
| Smoulders (Normal mode) [] | 1 | 1/76,800 |
| Sofiya [] | 1 | 1/33,554,432 |
| Soldier [] | 1 | 1/4,194,304 |
 Sorebones[] | 1 | 1/8,388,608 |
| Soulgazer [] | 1 | 1/51,200 |
| Soulgazer [] | 1 | 1/51,200 |
| Speedy Keith [] | 1 | 1/4,194,304 |
| Spiritual mage [] | 1 | 1/599,186.29 |
| Spiritual warrior [] | 1 | 1/1,198,372.57 |
| Spyndra (Normal mode) [] | 1 | 1/76,800 |
| Steel dragon [] | 1 | 1/1,398,101.33 |
| Stick [] | 1 | 1/1,677,721.6 |
| Suqah [] | 1 | 1/1,690,828.8 |
| Svetlana [] | 1 | 1/33,554,432 |
| Taraket the Necromancer (Normal mode) [] | 1 | 1/76,800 |
| Terror dog [] | 1 | 1/1,398,101.33 |
| The Ambassador (Normal mode) [] | 1 | 1/76,800 |