| Wyvern [] | 450–550 | 1/128,000 |
| Wyvern [] | 15–25 | 6/128, 3 rolls |
| Wyvern [] | 450–550 | 1/128,000, 3 rolls |
| Xiang the Water-shaper (Normal mode) [] | 450–550 | 1/192,000 |
| Yadviga [] | 450–550 | 1/83,886,080 |
| Yeti [] | 450–550 | 1/3,276,800 |
| Yor'Ger the Deceiver (Normal mode) [] | 450–550 | 1/192,000 |
| Yukimura of Hanto (Normal mode) [] | 450–550 | 1/192,000 |
| Yuri [] | 450–550 | 1/83,886,080 |
| Zamorak crafter [] | 3 | 2/70 |
 Zamorak, Lord of Chaos[] | 100–150 | 1/13 |
| Zamorakian cultist (Normal mode) [] | 10–20 | 1/74.1 |
| Zamorakian cultist (Normal mode) [] | 450–550 | 1/192,000 |
| Zamorakian cultist (Story mode) [] | 3–4 | 600/10,000 |
| Zamorakian hound master (Normal mode) [] | 10–20 | 1/74.1 |
| Zamorakian hound master (Normal mode) [] | 450–550 | 1/192,000 |
| Zamorakian hound master (Story mode) [] | 3–4 | 600/10,000 |
| Zamorakian hunter (Normal mode) [] | 10–20 | 1/74.1 |
| Zamorakian hunter (Normal mode) [] | 450–550 | 1/192,000 |
| Zamorakian hunter (Story mode) [] | 3–4 | 600/10,000 |
| Zamorakian ritual keeper (Level 107 (Normal mode)) [] | 10–20 | 1/74.1 |
| Zamorakian ritual keeper (Level 107 (Normal mode)) [] | 450–550 | 1/192,000 |
| Zamorakian ritual keeper (Level 107 (Story mode)) [] | 3–4 | 600/10,000 |
| Zamorakian ritual keeper (Level 115 (Normal mode)) [] | 10–20 | 1/74.1 |
| Zamorakian ritual keeper (Level 115 (Normal mode)) [] | 450–550 | 1/192,000 |
| Zamorakian ritual keeper (Level 115 (Story mode)) [] | 3–4 | 600/10,000 |
| Zamorakian sniper [] | 450–550 | 1/4,128,768 |
| Zoja [] | 450–550 | 1/83,886,080 |
| Zombie (Lair of Tarn Razorlor) (Levels 72–75) [] | 450–550 | 1/20,971,520 |
| Zombie (Lair of Tarn Razorlor) (Levels 77–79) [] | 450–550 | 1/20,971,520 |
| Zombie (Lair of Tarn Razorlor) (Levels 82–85) [] | 450–550 | 1/20,971,520 |
| Zombie (Stronghold of Security) [] | 450–550 | 1/8,192,000 |
| Zombie (Normal mode) [] | 450–550 | 1/192,000 |
| Zombie (Wilderness) (Level 29) [] | 450–550 | 1/20,971,520 |
| Zombie pirate [] | 450–550 | 1/20,971,520 |
| Zombie pirate (Harmony Island) [] | 450–550 | 1/20,971,520 |
| Zombie swab [] | 450–550 | 1/20,971,520 |
| Zombie (Level 29) [] | 450–550 | 1/20,971,520 |