Loot tables
- Sea horrorNormal mode (Section 1)
- Sea horrorNormal mode (Section 2)
- Sea horrorStory mode,Normal mode
- Sea troll
- Seagull
- Seagull10 feathers
- Seagull5 feathers
- SeagullDrops wing
- SeagullSarim 5 feathers
- Seasinger's equipmentSuperior armour
- Seaweed (Aquarium)
- Seaweed (Beneath Cursed Tides)
- Secure chest (Desert Treasure)
- Secure chest (Dorgesh-Kaan)
- Secure Chest (nature runes)
- Secure chest (Oldak)
- Secure chest (Zanik)
- Security booth
- Security casket (CS Week)
- Sedimentary geode
- Seed Stall
- Seed Stall (Draynor Village)
- Seeping elm tree
- Seers weathervane
- Seiryu the Azure SerpentNormal mode (Duo)
- Seiryu the Azure SerpentNormal mode (Solo)
- Seiryu the Azure SerpentNormal mode (Trio)
- Senntisten Dig Site (research)
- Senntisten soil
- Seren stone
- Serum 208 flask
- Shadow animica rock
- Shadow nihil
- Shadow Play
- Shadow Realm Sundering
- Shadow-Forger Ihlakhizan
- Shakroth remains
- Shark Attack
- Shark pool
- Shattered blade
- She Is Adamant
- Shelf (Shades of Mort'ton)
- Shelves (Meeting History)Tall
- Shelves (Old Tower)4, searchable
- Shelves (Old Tower)5, searchable
- Shelves (Requiem for a Dragon)
- Shelves (Senntisten Asylum)Twilight of the Gods
- Shelves (Sorceress's house)