| Dagannoth (Melee) [] | 1 | 1/467,331.92 |
| Dagannoth (Ranged) [] | 1 | 1/467,331.92 |
| Dark beast [] | 1 | 1/5,704.74 |
| Dark beast [] | 1 | 1/2,852.37, 3 rolls |
| Dark wizard (The Zamorakian Undercity) (Normal mode) [] | 1 | 1/4,278.55 |
| Dark wizard elder (Normal mode) [] | 1 | 1/4,278.55 |
| Dark wizard master (Normal mode) [] | 1 | 1/4,278.55 |
| Death Lotus rogue [] | 1 | 1/233,665.96 |
| Death Lotus rogue (Elite Dungeons) (Temple of Aminishi (Normal mode)) [] | 1 | 1/4,278.55 |
| Death Lotus rogue (Elite Dungeons) (The Shadow Reef (Normal mode)) [] | 1 | 1/4,278.55 |
| Deathbreath (Normal mode) [] | 1 | 1/4,278.55 |
| Demon Boss (Wilderness) [] | 1 | 1/64, 5 rolls |
| Desert lizard [] | 1 | 1/93,466.38 |
| Desert strykewyrm [] | 1 | 1/40,972.68 |
| Devil's snare [] | 1 | 1/2,852.37 |
| Donny the Lad [] | 1 | 1/233,665.96 |
| Dragon wolf alpha (Normal mode) [] | 1 | 1/4,278.55 |
| Dragonstone dragon [] | 1 | 1/4,278.55 |
| Dragonstone dragon (Dragonkin Laboratory) (Normal mode) [] | 1 | 1/4,278.55 |
| Dried zombie [] | 1 | 1/233,665.96 |
| Dust devil [] | 1 | 1/233,665.96 |
| Dust devil [] | 1 | 1/36,510.31, 3 rolls |
| Dwarf (Keldagrim and White Wolf Mountain) [] | 1 | 1/467,331.92 |
| Dwarf (Regular) [] | 1 | 1/467,331.92 |
| Earth elemental [] | 1 | 1/233,665.96 |
| Earth warrior [] | 1 | 1/233,665.96 |
| Earth warrior [] | 1 | 1/21,906.18, 3 rolls |
| Eastern mercenary (Normal mode) [] | 1 | 1/4,278.55 |
| Eastern soldier [] | 1 | 1/467,331.92 |
| Edimmu [] | 1 | 1/2,852.37 |
| Edimmu [] | 1 | 1/2,852.37 |
| Eduard [] | 1 | 1/1,869,327.69 |
| Elegorn the Celestial (Normal mode) [] | 1 | 1/4,278.55 |
| Elf warrior (Elf Camp) [] | 1 | 1/93,466.38 |
| Elf warrior (Lletya) [] | 1 | 1/93,466.38 |
| Elite Black Knight [] | 1 | 1/233,665.96 |
| Elite Dark Ranger [] | 1 | 1/467,331.92 |
| Elite Dark Warrior [] | 1 | 1/467,331.92 |
| Elite Khazard guard [] | 1 | 1/104,315.16 |
| Elite Profane Scabarite [] | 1 | 1/4,278.55 |
| Elite rune dragon [] | 1 | 1/285.24 |
| Elite Sakadagami (Normal mode) [] | 1 | 1/4,278.55 |
| Elite Sotapanna (Normal mode) [] | 1 | 1/4,278.55 |
| Emberbound Soul (Normal mode) [] | 1 | 1/4,278.55 |
| Engorged lava strykewyrm (Normal mode) [] | 1 | 1/4,278.55 |
| Enlightened Sotapanna (Normal mode) [] | 1 | 1/4,278.55 |
| Enraged barbarian spirit [] | 1 | 1/224,538.38 |
| Exiled kalphite guardian [] | 1 | 1/77,888.65 |