| Dagannoth spawn [] | 1 | 1/1,686,152.36 |
| Dagannoth Supreme [] | 1 | 1/14,383.69 |
| Dagannoth (Melee) [] | 1 | 1/1,686,152.36 |
| Dagannoth (Ranged) [] | 1 | 1/1,686,152.36 |
| Dark beast [] | 1 | 1/20,582.91 |
| Dark beast [] | 1 | 1/10,291.46, 3 rolls |
| Dark wizard (The Zamorakian Undercity) (Normal mode) [] | 1 | 1/15,437.19 |
| Dark wizard elder (Normal mode) [] | 1 | 1/15,437.19 |
| Dark wizard master (Normal mode) [] | 1 | 1/15,437.19 |
| Death Lotus rogue [] | 1 | 1/843,076.18 |
| Death Lotus rogue (Elite Dungeons) (Temple of Aminishi (Normal mode)) [] | 1 | 1/15,437.19 |
| Death Lotus rogue (Elite Dungeons) (The Shadow Reef (Normal mode)) [] | 1 | 1/15,437.19 |
| Deathbreath (Normal mode) [] | 1 | 1/15,437.19 |
| Demon Boss (Non-Wilderness) [] | 1 | 2/64, 5 rolls |
| Demon Boss (Wilderness) [] | 1 | 4/64, 5 rolls |
| Desert lizard [] | 1 | 1/337,230.47 |
| Desert strykewyrm [] | 1 | 1/147,831.07 |
| Devil's snare [] | 1 | 1/10,291.46 |
| Donny the Lad [] | 1 | 1/843,076.18 |
 Dragon impling[] | 1 | 1/18 |
| Dragon impling jar [] | 1 | 1/18 |
| Dragon wolf alpha (Normal mode) [] | 1 | 1/15,437.19 |
| Dragonstone dragon [] | 1 | 1/15,437.19 |
| Dragonstone dragon (Dragonkin Laboratory) (Normal mode) [] | 1 | 1/15,437.19 |
| Dried zombie [] | 1 | 1/843,076.18 |
| Dust devil [] | 1 | 1/843,076.18 |
| Dust devil [] | 1 | 1/131,730.65, 3 rolls |
| Dwarf (Keldagrim and White Wolf Mountain) [] | 1 | 1/1,686,152.36 |
| Dwarf (Regular) [] | 1 | 1/1,686,152.36 |
| Earth elemental [] | 1 | 1/843,076.18 |
| Earth warrior [] | 1 | 1/843,076.18 |
| Earth warrior [] | 1 | 1/79,038.39, 3 rolls |
| Eastern mercenary (Normal mode) [] | 1 | 1/15,437.19 |
| Eastern soldier [] | 1 | 1/1,686,152.36 |
| Edimmu [] | 1 | 1/10,291.46 |
| Edimmu [] | 1 | 1/10,291.46 |
| Eduard [] | 1 | 1/6,744,609.45 |
| Elegorn the Celestial (Normal mode) [] | 1 | 1/15,437.19 |
| Elf warrior (Elf Camp) [] | 1 | 1/337,230.47 |
| Elf warrior (Lletya) [] | 1 | 1/337,230.47 |
| Elite Black Knight [] | 1 | 1/843,076.18 |
| Elite Dark Ranger [] | 1 | 1/1,686,152.36 |
| Elite Dark Warrior [] | 1 | 1/1,686,152.36 |
| Elite Khazard guard [] | 1 | 1/376,373.3 |
| Elite Profane Scabarite [] | 1 | 1/15,437.19 |
| Elite rune dragon [] | 1 | 5/128 |
| Elite rune dragon [] | 1 | 1/1,029.15 |
| Elite Sakadagami (Normal mode) [] | 1 | 1/15,437.19 |