| Crassian Leviathan (Normal mode) [] | 1 | 1/1,600 |
| Crassian scout (Normal mode) [] | 1 | 1/1,600 |
| Crassian scuttler (Normal mode) [] | 1 | 1/1,600 |
| Crassian warrior (Normal mode) [] | 1 | 1/1,600 |
| Crawling hand [] | 1 | 1/7,489.83 |
| Crocodile akh [] | 1 | 1/1,600 |
| Crystal chest [] | 1 | 500/6,801 |
| Crystal chest (Prifddinas) [] | 1 | 600/6,801 |
 Crystal impling[] | 1 | 70/500 |
| Crystal impling jar [] | 1 | 70/500 |
| Crystal Shapeshifter (Magic) [] | 1 | 1/1,600 |
| Cyclops [] | 1 | 1/5,851.43 |
| Cyclops [] | 1 | Very rare |
| Cyclops (God Wars Dungeon) [] | 1 | 1/5,851.43 |
| Cyclossus [] | 1 | 1/2,133.33 |
| Dagannoth (Lighthouse) [] | 1 | 1/14,979.66 |
| Dagannoth guardian [] | 1 | 1/1,872.46 |
| Dagannoth Prime [] | 1 | 1/862.77 |
| Dagannoth Rex [] | 1 | 1/862.77 |
| Dagannoth spawn [] | 1 | 1/14,979.66 |
| Dagannoth Supreme [] | 1 | 1/862.77 |
| Dagannoth (Melee) [] | 1 | 1/14,979.66 |
| Dagannoth (Ranged) [] | 1 | 1/14,979.66 |
| Dark beast [] | 1 | 1/2,133.33 |
| Dark beast [] | 1 | 1/1,066.67, 3 rolls |
| Dark wizard (The Zamorakian Undercity) (Normal mode) [] | 1–2 | 1/33.3 |
| Dark wizard (The Zamorakian Undercity) (Normal mode) [] | 1 | 1/1,600 |
| Dark wizard (The Zamorakian Undercity) (Story mode) [] | 1 | 200/10,000 |
| Dark wizard elder (Normal mode) [] | 1–2 | 1/33.3 |
| Dark wizard elder (Normal mode) [] | 1 | 1/1,600 |
| Dark wizard elder (Story mode) [] | 1 | 200/10,000 |
| Dark wizard master (Normal mode) [] | 1–2 | 1/33.3 |
| Dark wizard master (Normal mode) [] | 1 | 1/1,600 |
| Dark wizard master (Story mode) [] | 1 | 200/10,000 |
| Death Lotus rogue [] | 1 | 1/7,489.83 |
| Death Lotus rogue (Elite Dungeons) (Temple of Aminishi (Normal mode)) [] | 1 | 1/1,600 |
| Death Lotus rogue (Elite Dungeons) (The Shadow Reef (Normal mode)) [] | 1 | 1/1,600 |
| Deathbreath (Normal mode) [] | 1 | 1/1,600 |
| Desert lizard [] | 1 | 1/2,995.93 |
| Desert strykewyrm [] | 1 | 1/1,313.32 |
| Devil's snare [] | 1 | 1/1,066.67 |
| Donny the Lad [] | 1 | 1/7,489.83 |
| Dragon wolf alpha (Normal mode) [] | 1 | 1/1,600 |
| Dragonstone dragon [] | 1 | 1/1,600 |
| Dragonstone dragon (Dragonkin Laboratory) (Normal mode) [] | 1 | 1/1,600 |
| Dried zombie [] | 1 | 1/7,489.83 |
| Dust devil [] | 1 | 1/7,489.83 |
| Dust devil [] | 1 | 1/1,170.29, 3 rolls |