| Dagannoth spawn [] | 90–150 | 1/7,989,150.48 |
| Dagannoth Supreme [] | 90–150 | 1/68,151.31 |
| Dagannoth (Melee) [] | 90–150 | 1/7,989,150.48 |
| Dagannoth (Ranged) [] | 90–150 | 1/7,989,150.48 |
| Dark beast [] | 90–150 | 1/97,523.81 |
| Dark beast [] | 90–150 | 1/48,761.9, 3 rolls |
| Dark wizard (The Zamorakian Undercity) (Normal mode) [] | 90–150 | 1/73,142.86 |
| Dark wizard elder (Normal mode) [] | 90–150 | 1/73,142.86 |
| Dark wizard master (Normal mode) [] | 90–150 | 1/73,142.86 |
| Death Lotus rogue [] | 90–150 | 1/3,994,575.24 |
| Death Lotus rogue (Elite Dungeons) (Temple of Aminishi (Normal mode)) [] | 90–150 | 1/73,142.86 |
| Death Lotus rogue (Elite Dungeons) (The Shadow Reef (Normal mode)) [] | 90–150 | 1/73,142.86 |
| Deathbreath (Normal mode) [] | 90–150 | 1/73,142.86 |
| Desert lizard [] | 90–150 | 1/1,597,830.1 |
| Desert strykewyrm [] | 90–150 | 1/700,437.67 |
| Devil's snare [] | 90–150 | 1/48,761.9 |
| Donny the Lad [] | 90–150 | 1/3,994,575.24 |
| Dragon wolf alpha (Normal mode) [] | 90–150 | 1/73,142.86 |
| Dragonstone dragon [] | 90–150 | 1/73,142.86 |
| Dragonstone dragon (Dragonkin Laboratory) (Normal mode) [] | 90–150 | 1/73,142.86 |
| Dried zombie [] | 90–150 | 1/3,994,575.24 |
| Dust devil [] | 90–150 | 1/3,994,575.24 |
| Dust devil [] | 90–150 | 1/624,152.38, 3 rolls |
| Dwarf (Keldagrim and White Wolf Mountain) [] | 90–150 | 1/7,989,150.48 |
| Dwarf (Regular) [] | 90–150 | 1/7,989,150.48 |
| Earth elemental [] | 90–150 | 1/3,994,575.24 |
| Earth warrior [] | 90–150 | 1/3,994,575.24 |
| Earth warrior [] | 90–150 | 1/374,491.43, 3 rolls |
| Eastern mercenary (Normal mode) [] | 90–150 | 1/73,142.86 |
| Eastern soldier [] | 90–150 | 1/7,989,150.48 |
| Edimmu [] | 3–5 | 8/128 |
| Edimmu [] | 90–150 | 1/48,761.9 |
| Edimmu [] | 90–150 | 1/48,761.9 |
| Eduard [] | 90–150 | 1/31,956,601.9 |
| Elegorn the Celestial (Normal mode) [] | 90–150 | 1/73,142.86 |
| Elf warrior (Elf Camp) [] | 90–150 | 1/1,597,830.1 |
| Elf warrior (Lletya) [] | 90–150 | 1/1,597,830.1 |
| Elite Black Knight [] | 90–150 | 1/3,994,575.24 |
| Elite Dark Ranger [] | 90–150 | 1/7,989,150.48 |
| Elite Dark Warrior [] | 90–150 | 1/7,989,150.48 |
| Elite Khazard guard [] | 90–150 | 1/1,783,292.52 |
| Elite Profane Scabarite [] | 6 | 40/1,024 |
| Elite Profane Scabarite [] | 90–150 | 1/73,142.86 |
| Elite rune dragon [] | 90–150 | 1/4,876.19 |
| Elite Sakadagami (Normal mode) [] | 90–150 | 1/73,142.86 |
| Elite Sotapanna (Normal mode) [] | 90–150 | 1/73,142.86 |
| Emberbound Soul (Normal mode) [] | 90–150 | 1/73,142.86 |
| Engorged lava strykewyrm (Normal mode) [] | 90–150 | 1/73,142.86 |