| Cyclossus [] | 67–85 | 1/136,533.33 |
| Dagannoth (Lighthouse) [] | 67–85 | 1/11,184,810.67 |
| Dagannoth guardian [] | 67–85 | 1/1,398,101.33 |
| Dagannoth Prime [] | 67–85 | 1/95,411.83 |
| Dagannoth Rex [] | 67–85 | 1/95,411.83 |
| Dagannoth spawn [] | 67–85 | 1/11,184,810.67 |
| Dagannoth Supreme [] | 67–85 | 1/95,411.83 |
| Dagannoth (Melee) [] | 67–85 | 1/11,184,810.67 |
| Dagannoth (Ranged) [] | 67–85 | 1/11,184,810.67 |
| Dark beast [] | 67–85 | 1/136,533.33 |
| Dark beast [] | 67–85 | 1/68,266.67, 3 rolls |
| Dark wizard (The Zamorakian Undercity) (Normal mode) [] | 67–85 | 1/102,400 |
| Dark wizard elder (Normal mode) [] | 67–85 | 1/102,400 |
| Dark wizard master (Normal mode) [] | 67–85 | 1/102,400 |
| Death Lotus rogue [] | 67–85 | 1/5,592,405.33 |
| Death Lotus rogue (Elite Dungeons) (Temple of Aminishi (Normal mode)) [] | 67–85 | 1/102,400 |
| Death Lotus rogue (Elite Dungeons) (The Shadow Reef (Normal mode)) [] | 67–85 | 1/102,400 |
| Deathbreath (Normal mode) [] | 67–85 | 1/102,400 |
| Desert lizard [] | 67–85 | 1/2,236,962.13 |
| Desert strykewyrm [] | 67–85 | 1/980,612.74 |
| Devil's snare [] | 67–85 | 1/68,266.67 |
| Donny the Lad [] | 67–85 | 1/5,592,405.33 |
| Dragon wolf alpha (Normal mode) [] | 67–85 | 1/102,400 |
| Dragonstone dragon [] | 67–85 | 1/102,400 |
| Dragonstone dragon (Dragonkin Laboratory) (Normal mode) [] | 67–85 | 1/102,400 |
| Dried zombie [] | 67–85 | 1/5,592,405.33 |
| Dust devil [] | 67–85 | 1/5,592,405.33 |
| Dust devil [] | 67–85 | 1/873,813.33, 3 rolls |
| Dwarf (Keldagrim and White Wolf Mountain) [] | 67–85 | 1/11,184,810.67 |
| Dwarf (Regular) [] | 67–85 | 1/11,184,810.67 |
| Earth elemental [] | 67–85 | 1/5,592,405.33 |
| Earth warrior [] | 67–85 | 1/5,592,405.33 |
| Earth warrior [] | 67–85 | 1/524,288, 3 rolls |
| Eastern mercenary (Normal mode) [] | 67–85 | 1/102,400 |
| Eastern soldier [] | 67–85 | 1/11,184,810.67 |
| Edimmu [] | 67–85 | 1/68,266.67 |
| Edimmu [] | 67–85 | 1/68,266.67 |
| Eduard [] | 1 | 2/512 |
| Eduard [] | 67–85 | 1/44,739,242.67 |
| Elegorn the Celestial (Normal mode) [] | 67–85 | 1/102,400 |
| Elf warrior (Elf Camp) [] | 67–85 | 1/2,236,962.13 |
| Elf warrior (Lletya) [] | 67–85 | 1/2,236,962.13 |
| Elite Black Knight [] | 67–85 | 1/5,592,405.33 |
| Elite Dark Ranger [] | 67–85 | 1/11,184,810.67 |
| Elite Dark Warrior [] | 67–85 | 1/11,184,810.67 |
| Elite Khazard guard [] | 67–85 | 1/2,496,609.52 |
| Elite Profane Scabarite [] | 67–85 | 1/102,400 |
| Elite rune dragon [] | 67–85 | 1/6,826.67 |