| Corrupted dust devil [] | 450–550 | 1/192,000 |
| Corrupted kalphite guardian [] | 450–550 | 1/192,000 |
| Corrupted kalphite marauder [] | 450–550 | 1/192,000 |
| Corrupted lizard [] | 450–550 | 1/192,000 |
| Corrupted scarab [] | 450–550 | 1/192,000 |
| Corrupted scorpion [] | 450–550 | 1/192,000 |
| Corrupted worker [] | 450–550 | 1/192,000 |
| Crassian Leviathan (Normal mode) [] | 450–550 | 1/192,000 |
| Crassian scout (Normal mode) [] | 450–550 | 1/192,000 |
| Crassian scuttler (Normal mode) [] | 450–550 | 1/192,000 |
| Crassian warrior (Normal mode) [] | 450–550 | 1/192,000 |
| Crawling hand [] | 450–550 | 1/10,485,760 |
| Crocodile akh [] | 450–550 | 1/192,000 |
| Croesus (Active) [] | 120–180 | 40/1,000 |
| Crystal Shapeshifter (Magic) [] | 450–550 | 1/192,000 |
| Cyclops [] | 450–550 | 1/8,192,000 |
| Cyclops [] | 450–550 | Very rare |
| Cyclops (God Wars Dungeon) [] | 450–550 | 1/8,192,000 |
| Cyclossus [] | 450–550 | 1/256,000 |
| Dagannoth (Lighthouse) [] | 450–550 | 1/20,971,520 |
| Dagannoth guardian [] | 450–550 | 1/2,621,440 |
| Dagannoth Prime [] | 450–550 | 1/178,897.18 |
| Dagannoth Rex [] | 450–550 | 1/178,897.18 |
| Dagannoth spawn [] | 450–550 | 1/20,971,520 |
| Dagannoth Supreme [] | 450–550 | 1/178,897.18 |
| Dagannoth (Melee) [] | 450–550 | 1/20,971,520 |
| Dagannoth (Ranged) [] | 450–550 | 1/20,971,520 |
| Dark beast [] | 450–550 | 1/256,000 |
| Dark beast [] | 450–550 | 1/128,000, 3 rolls |
| Dark wizard (The Zamorakian Undercity) (Normal mode) [] | 10–20 | 1/20.2 |
| Dark wizard (The Zamorakian Undercity) (Normal mode) [] | 450–550 | 1/192,000 |
| Dark wizard (The Zamorakian Undercity) (Story mode) [] | 3–4 | 600/10,000 |
| Dark wizard elder (Normal mode) [] | 10–20 | 1/21.4 |
| Dark wizard elder (Normal mode) [] | 450–550 | 1/192,000 |
| Dark wizard elder (Story mode) [] | 3–4 | 600/10,000 |
| Dark wizard master (Normal mode) [] | 10–20 | 1/22.2 |
| Dark wizard master (Normal mode) [] | 450–550 | 1/192,000 |
| Dark wizard master (Story mode) [] | 3–4 | 600/10,000 |
| Darkmeyer magic stall [] | 5–10 | 213/1,200 |
| Death Lotus rogue [] | 450–550 | 1/10,485,760 |
| Death Lotus rogue (Elite Dungeons) (Temple of Aminishi (Normal mode)) [] | 450–550 | 1/192,000 |
| Death Lotus rogue (Elite Dungeons) (The Shadow Reef (Normal mode)) [] | 450–550 | 1/192,000 |
| Deathbreath (Normal mode) [] | 450–550 | 1/192,000 |
| Desert lizard [] | 450–550 | 1/4,194,304 |
| Desert strykewyrm [] | 450–550 | 1/1,838,648.89 |
| Devil's snare [] | 450–550 | 1/128,000 |
| Donny the Lad [] | 450–550 | 1/10,485,760 |
| Dragon wolf alpha (Normal mode) [] | 450–550 | 1/192,000 |